• Comprehensive Pest Protection

    K9 Advantix II effectively protects your dog from fleas, ticks, mosquitoes, biting flies, and lice.

  • Fast-Acting Flea Control

    This treatment begins killing fleas within 12 hours of application.

  • Contact Kill & Repel

    Its vet-recommended formula works by killing and repelling pests on contact, preventing them from needing to bite your dog.

    K9 Advantix ||

    K9 Advantix II Large Dog Flea & Tick Treatment – 6 Month Supply
    -11%

    K9 Advantix II Large Dog Flea & Tick Treatment – 6 Month Supply

    Give your dog the protection they deserve with K9 Advantix II for Large Dogs, the #1 vet-recommen...

    (23)
    $71.17 $79.97
    K9 Advantix II Dogs Over 55 lbs Flea & Tick Treatment – 6 Month Supply
    -11%

    K9 Advantix II Dogs Over 55 lbs Flea & Tick Treatment – 6 Month Supply

    Protect your big dog from fleas, ticks, and mosquitoes with K9 Advantix II for Extra-Large Dogs, ...

    (46)
    $71.17 $79.97
    K9 Advantix II Medium Dog 11–20 lbs Flea & Tick Treatment – 6 Month Supply
    -11%

    K9 Advantix II Medium Dog 11–20 lbs Flea & Tick Treatment – 6 Month Supply

    Give your dog complete, vet-trusted protection with K9 Advantix II for Medium Dogs — the powerful...

    (69)
    $71.19 $79.99

    K9 Advantix II Features

    Easy Topical Application: The treatment is a simple-to-apply topical solution, making it convenient for pet owners.

    Fragrance-Free Formula: K9 Advantix II is fragrance-free, avoiding any strong odors that might bother you or your dog.

    Waterproof Protection: This treatment remains effective and waterproof after 24 hours, allowing your dog to enjoy water activities.

    No Prescription Needed: You can purchase K9 Advantix II without a veterinary prescription, offering convenient access to effective pest control.

    Targeted Dosing by Weight: Available in specific formulations for Extra Large, Large, and Small dogs, ensuring appropriate and effective treatment for your dog’s size.

    Active Ingredients Imidacloprid and Permethrin: Contains a powerful combination of active ingredients to provide effective pest control.

    Shop K9 Advantix ||
    • Sharon Roberts

      I’ve been using K9 Advantix II for years, and it’s truly a lifesaver for my Golden Retriever! Even with his long, thick fur, this product keeps him completely free of fleas, ticks, and mosquitoes during peak season. It works wonders, and I always keep some on hand for those unexpected emergencies.

    • Larry Wilson

      Advantix II is by far the most effective flea and tick treatment I’ve used for my dog, especially against those pesky mosquitoes that are a constant threat here. While some topicals can be a bit strong, I’ve found that spreading the application out makes all the difference for her sensitive skin. It’s a fantastic product that truly delivers on its promise of protection.

    • Patricia Collins

      Before K9 Advantix II, my dog was constantly scratching and just miserable. I’m so thrilled that after trying numerous products, this one finally brought her relief within 24 hours! It’s incredibly easy to apply and gives me immense peace of mind knowing she’s protected from so many different pests. This product has truly improved her comfort and overall happiness.

      Video Reviews

      About K9 Advantix II

      About Us

      At K9 Advantix II, we’re passionate about helping you provide the best possible care for your beloved canine companion. We understand that a happy, healthy dog is at the heart of every family, and that’s why we’re dedicated to offering effective and reliable solutions for pest prevention. Our commitment extends beyond just our products; we’ve spent countless hours developing and improving our official website to be a valuable resource for pet owners like you.

      Our team has meticulously designed this website with your needs in mind, striving to create an intuitive and informative online experience. For example, we’ve refined our navigation to help you easily find the right K9 Advantix II product for your dog’s size, whether it’s our XL, Large, or Small dog formulations. We’ve also enhanced sections like our “Features” and “Testimonials” to provide clear, concise information and real-world success stories, ensuring you have all the details needed to make informed decisions about your dog’s protection. We believe that empowering you with knowledge is key to helping your dog live a life free from the nuisance and danger of fleas, ticks, and mosquitoes.

      Our History

      K9 Advantix II has a proud history rooted in a deep understanding of animal health, originating from the extensive research and development within Bayer Animal Health, a renowned name in veterinary medicine. Our journey in providing advanced pest protection for dogs began with a commitment to scientific innovation and a dedication to animal well-being. Today, K9 Advantix II is part of the Elanco Animal Health portfolio, a global leader in animal health that continues to build upon a legacy of nearly 70 years in empowering veterinarians, farmers, and pet owners with cutting-edge solutions. This evolution ensures that K9 Advantix II remains at the forefront of flea, tick, and mosquito prevention, continuously striving to give your dog the comprehensive protection they deserve.