Frontline Plus for Large Dogs (45–88 lbs) – Flea & Tick Treatment

Frontline Plus for Large Dogs (45–88 lbs) – Flea & Tick Treatment

$66.73
$66.73 $74.98
SAVE 11% Sold out

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Frontline Plus for Large Dogs (45–88 lbs) – Flea & Tick Treatment

Frontline Plus for Large Dogs (45–88 lbs) – Flea & Tick Treatment

$66.73
$66.73 $74.98
SAVE 11% Sold out

Protect your large dog with Frontline Plus, a veterinarian-recommended flea and tick treatment for dogs weighing 45 to 88 lbs. This fast-acting, waterproof formula kills adult fleas, ticks, and chewing lice, and stops flea infestations by eliminating eggs and larvae.

Each dose offers up to 30 days of protection, and this 3-month supply ensures long-lasting defense against pests. Simple to apply and trusted by pet owners for over two decades.

🐶 Key Benefits:

  • Kills fleas, flea eggs, ticks, and lice
  • Waterproof and fast-acting formula
  • Safe for dogs 45–88 lbs, 8 weeks and older
  • Vet-recommended for over 20 years
  • 3 doses = 3-month protection

💙 Available now at Frontlines – your partner in keeping pets protected, healthy, and happy.

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Advanced Flea, Tick & Lice Protection You Can Trust

Keep your cats and dogs protected with a proven formula designed to eliminate fleas, ticks, flea eggs, flea larvae, and chewing lice. Trusted by pet owners for fast-acting, reliable monthly protection.

Trusted Protection. Everyday Comfort.

Keep your pets protected from fleas and ticks with a long-lasting solution that's simple to use, veterinarian recommended, and designed for everyday comfort.

Month-Long Protection in Just One Application

Keep your dog protected from fleas, ticks, mosquitoes, and biting flies with a fast-acting formula that delivers reliable protection for up to 30 days.

Compare Our Trusted Flea & Tick Protection Brands

Find the right flea and tick protection by comparing the key benefits of our most trusted pet care brands.

Features Frontline Plus Advantage II K9 Advantix II Seresto
Kills adult fleas
Kills flea eggs
Kills flea larvae
Protects against ticks
Repels mosquitoes
Repels biting flies
Kills chewing lice
Waterproof protection
Monthly topical treatment
Up to 8 months protection
Easy to apply
Suitable for cats
Suitable for dogs

    Frontline Plus

    Frontline Plus helps protect cats from fleas, flea eggs, flea larvae, chewing lice, and ticks. It also helps break the flea life cycle by preventing future infestations.
    Apply one dose every 30 days for continuous flea and tick protection. Regular monthly treatment provides the best results.
    Yes. Frontline Plus for Cats is suitable for kittens 8 weeks of age and older that meet the minimum weight requirements listed on the package.

    Seresto

    Seresto provides continuous flea and tick protection for up to 8 months without the need for monthly applications.
    Yes. Seresto remains effective after occasional exposure to water, including rain and bathing, although excessive water exposure may shorten its effectiveness.
    Yes. The collar is designed for continuous wear and should remain on your pet to maintain uninterrupted protection.

    Advantage II

    Advantage II kills adult fleas, flea larvae, and flea eggs to help stop flea infestations quickly and effectively.
    Advantage II begins killing fleas within hours after application and continues protecting your cat for up to one month.
    Yes. Indoor cats can also be exposed to fleas, making monthly flea prevention an important part of their health care.

    K9 Advantix II

    K9 Advantix II helps protect dogs against fleas, ticks, mosquitoes, biting flies, and lice.
    No. K9 Advantix II is formulated only for dogs and should never be used on cats.
    Apply one treatment every month to maintain continuous protection against fleas, ticks, mosquitoes, and other listed pests.